{"id":2603,"date":"2022-09-02T13:15:33","date_gmt":"2022-09-02T12:15:33","guid":{"rendered":"https:\/\/www.hilotherm.com\/areas-of-application\/polyneuropathy\/"},"modified":"2025-09-12T13:13:17","modified_gmt":"2025-09-12T12:13:17","slug":"polyneuropathy","status":"publish","type":"page","link":"https:\/\/www.hilotherm.com\/en\/areas-of-application\/polyneuropathy\/","title":{"rendered":"Polyneuropathy"},"content":{"rendered":"<section class=\"l-section wpb_row us_custom_dda056cf height_auto with_img\"><div class=\"l-section-img\" role=\"img\" aria-label=\"Einsatzgebiet der Hilotherapie bei Polyneuropathie (CIPN) und das Hand-Fu\u00df- Syndrom (HFS)\" data-img-width=\"2559\" data-img-height=\"1120\" style=\"background-image: url(https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/06\/Titel_Gelb.jpg);background-position: center right;background-repeat: no-repeat;background-size: contain;\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_large\"><\/div><div class=\"w-separator size_large\"><\/div><div class=\"w-separator size_large\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h1><span style=\"color: #ffffff;\">HILOTHERAPY<sup>\u00ae<\/sup> ChemoCare <sup>CIPN<\/sup><\/span><\/h1>\n<h2>Prevention of Polyneuropathy\/Nerve Damage (CIPN) and Hand-Foot Syndrome (HFS)<\/h2>\n<\/div><\/div><div class=\"w-separator size_large\"><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h2 style=\"text-align: center;\"><span style=\"color: #f7db49;\">HILOTHERAPY<sup>\u00ae<\/sup> ChemoCare <sup>CIPN<\/sup><\/span><\/h2>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h2>The effective cooling treatment<\/h2>\n<p>HILOTHERAPY<sup>\u00ae<\/sup> is a physical cooling-treatment. With it&#8217;s degree-precise cooling mechanism for hand and feet it is applied in onocology to prevent side effects of chemotherapies. The HILOTHERAPY\u00ae prevents painful and often times irreversible chemotherapy-induced polyneuropathy (CIPN) or hand-foot-syndrome (HFS).<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image align_center\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"292\" height=\"300\" src=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/11\/hilotherapie_hilotherm_einsatzgebiete.png\" class=\"attachment-medium size-medium\" alt=\"Hilotherm Ger\u00e4te Einsatzgebiete\" loading=\"lazy\" \/><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium color_alternate with_img\"><div class=\"l-section-img\" role=\"img\" aria-label=\"Image\" data-img-width=\"1920\" data-img-height=\"1280\" style=\"background-image: url(https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/problem.jpg);\"><\/div><div class=\"l-section-overlay\" style=\"background:var(--color-header-transparent-text)\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h2><span style=\"color: #f7db49;\">The problem:<\/span><\/h2>\n<h3>Diagnosis cancer \u2013 chemotherapy \u2013 CIPN<\/h3>\n<\/div><\/div><div class=\"w-separator size_medium\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Despite innovative targeted therapy approaches, chemotherapy is still one of the most important therapeutic components in the treatment of cancer. It contributes to improving the long-term prognosis of oncological patients, but also causes side effects. Chemotherapy-induced polyneuropathy (CIPN) is a frequent complication of many antineoplastic system therapies.<\/p>\n<\/div><\/div><div class=\"w-separator size_medium\"><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><div class=\"g-cols wpb_row us_custom_d87a9e89 via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-4 wpb_column vc_column_container\"><div class=\"vc_column-inner us_custom_bb7967fc\"><div class=\"vc_column-overlay\" style=\"background:var(--color-header-transparent-text)\"><\/div><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>The danger: CIPN &gt; Grade 2<\/h3>\n<ul>\n<li>Therapy postponement<\/li>\n<li>Dose reduction<\/li>\n<li>Termination of therapy<\/li>\n<li>Deterioration of the long-term prognosis (outcome)<\/li>\n<li>Deterioration of quality of life for many years and often irreversible<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-4 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><div class=\"vc_col-sm-4 wpb_column vc_column_container\"><div class=\"vc_column-inner us_custom_bb7967fc\"><div class=\"vc_column-overlay\" style=\"background:rgba(247,219,73,0.80)\"><\/div><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>Studies show: high incidence rates.<\/h3>\n<p><strong>The incidence rate of CIPN (grades 1-3) is significantly higher than previously thought, at 74.4% (Blackley et al, 2019).<\/strong><\/p>\n<ul>\n<li>33% grade 2\/3 toxicities with three weeks of Taxol administration (Seidmann et al., JCO 2008)<\/li>\n<li>51% grade 2\/3 toxicities with weekly paclitaxel administration (Seidmann et al., JCO 2008)<\/li>\n<li>27% \u2265 grade 2 toxicities with paclitaxel weekly (Sparano et al., N Engl J Med 2008)<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_small color_primary\"><div class=\"l-section-overlay\" style=\"background:#F7DB49\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-actionbox color_primary controls_right\"><div class=\"w-actionbox-text\"><h3 class=\"w-actionbox-title\">Any further questions or further enquiries?<\/h3><\/div><div class=\"w-actionbox-controls\"><a class=\"w-btn us-btn-style_2\" href=\"https:\/\/www.hilotherm.com\/en\/?page_id=2173\" style=\"font-size:18px;\"><span class=\"w-btn-label\">Find a doctor<\/span><\/a><a class=\"w-btn us-btn-style_2\" title=\"Contact\" href=\"https:\/\/bzd6np.myraidbox.de\/kontakt\/\" style=\"font-size:18px;\" target=\"_blank\" rel=\"noopener\"><span class=\"w-btn-label\">Contact<\/span><\/a><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium with_img\"><div class=\"l-section-img\" role=\"img\" aria-label=\"Image\" data-img-width=\"1920\" data-img-height=\"1280\" style=\"background-image: url(https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/cipn_loesung.jpg);\"><\/div><div class=\"l-section-overlay\" style=\"background:rgba(255,255,255,0.8)\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_medium\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h2><span style=\"color: #f7db49;\">The Solution:<\/span><\/h2>\n<h3>HILOTHERM<sup>\u00ae <\/sup>ChemoCare<sup> CIPN<\/sup><\/h3>\n<h3>Controlled cooling of the extremities during chemotherapy.<\/h3>\n<h3><\/h3>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><div class=\"g-cols wpb_row us_custom_ac7252c9 via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-4 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3 style=\"text-align: left;\"><span style=\"color: #f7db49;\">HILOTHERAPY<sup>\u00ae<\/sup><\/span><\/h3>\n<p style=\"text-align: left;\">The world&#8217;s first processor-controlled hand\/foot cooling to prevent CIPN<\/p>\n<\/div><\/div><div class=\"w-separator size_medium\"><\/div><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"856\" height=\"1024\" src=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/cipn_anwendungen-856x1024.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/cipn_anwendungen-856x1024.png 856w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/cipn_anwendungen-251x300.png 251w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/cipn_anwendungen-125x150.png 125w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/cipn_anwendungen-600x718.png 600w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/cipn_anwendungen.png 1015w\" sizes=\"auto, (max-width: 856px) 100vw, 856px\" \/><\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-4 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><div class=\"vc_col-sm-4 wpb_column vc_column_container\"><div class=\"vc_column-inner us_custom_bb7967fc\"><div class=\"vc_column-overlay\" style=\"background:rgba(247,219,73,0.80)\"><\/div><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>Advantages:<\/h3>\n<\/div><\/div><div class=\"w-iconbox iconpos_left style_circle color_custom align_left no_title\"><div class=\"w-iconbox-icon\" style=\"font-size:1rem;--icon-color:#f7db49;--icon-bg-color:#ffffff;\"><i class=\"fas fa-plus\"><\/i><\/div><div class=\"w-iconbox-meta\"><div class=\"w-iconbox-text\"><p>Processor-controlled thermal process accurate to the degree<\/p>\n<\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-iconbox iconpos_left style_circle color_custom align_left no_title\"><div class=\"w-iconbox-icon\" style=\"font-size:1rem;--icon-color:#f7db49;--icon-bg-color:#ffffff;\"><i class=\"fas fa-plus\"><\/i><\/div><div class=\"w-iconbox-meta\"><div class=\"w-iconbox-text\"><p>constant cooling of the hands and feet with moderate coldness<\/p>\n<\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-iconbox iconpos_left style_circle color_custom align_left no_title\"><div class=\"w-iconbox-icon\" style=\"font-size:1rem;--icon-color:#f7db49;--icon-bg-color:#ffffff;\"><i class=\"fas fa-plus\"><\/i><\/div><div class=\"w-iconbox-meta\"><div class=\"w-iconbox-text\"><p>Oxygen demand of the tissue, metabolism as well as blood circulation are reduced<\/p>\n<\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-iconbox iconpos_left style_circle color_custom align_left no_title\"><div class=\"w-iconbox-icon\" style=\"font-size:1rem;--icon-color:#f7db49;--icon-bg-color:#ffffff;\"><i class=\"fas fa-plus\"><\/i><\/div><div class=\"w-iconbox-meta\"><div class=\"w-iconbox-text\"><p>reduced uptake of cytotoxic substances into the nerve endings &#8211; Reduction of nerve damage<\/p>\n<\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-iconbox iconpos_left style_circle color_custom align_left no_title\"><div class=\"w-iconbox-icon\" style=\"font-size:1rem;--icon-color:#f7db49;--icon-bg-color:#ffffff;\"><i class=\"fas fa-plus\"><\/i><\/div><div class=\"w-iconbox-meta\"><div class=\"w-iconbox-text\"><p>Pain receptors are positively influenced &#8211; pain relief<\/p>\n<\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium with_img\"><div class=\"l-section-img\" role=\"img\" aria-label=\"Image\" data-img-width=\"2560\" data-img-height=\"1707\" style=\"background-image: url(https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/cipn-wirksamkeit-bg-scaled.jpg);background-position: top right;background-repeat: no-repeat;background-size: contain;\"><\/div><div class=\"l-section-overlay\" style=\"background:var(--color-header-transparent-text)\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_medium\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h2 style=\"text-align: left;\"><span style=\"color: #f7db49;\">Efficacy:<\/span><\/h2>\n<h3>Our data prove the prophylactic effectiveness of HILOTHERAPY<sup>\u00ae<\/sup>.<\/h3>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Without prophylactic HILOTHERAPY<sup>\u00ae<\/sup> 90% of all patients inside develop symptoms of CIPN and Hand-Foot-Syndrom (Grade 1 &#8211; 3) \u2013 50% of them severe (Grade 2\/3).<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"226\" src=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/toxizitaet_2-1024x226.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/toxizitaet_2-1024x226.png 1024w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/toxizitaet_2-300x66.png 300w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/toxizitaet_2-250x55.png 250w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/toxizitaet_2-600x132.png 600w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/08\/toxizitaet_2.png 1586w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/div><\/div><div class=\"w-separator size_large\"><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><div class=\"g-cols wpb_row us_custom_cb930a70 via_flex valign_bottom type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner us_custom_67e116bf\"><div class=\"vc_column-overlay\" style=\"background:rgba(247,219,73,0.80)\"><\/div><div class=\"wpb_wrapper\"><div class=\"w-separator size_small\"><\/div><div class=\"w-iconbox iconpos_left style_circle color_custom align_left\"><div class=\"w-iconbox-icon\" style=\"font-size:1rem;--icon-color:#f7db49;--icon-bg-color:#ffffff;\"><i class=\"fas fa-plus\"><\/i><\/div><div class=\"w-iconbox-meta\"><h5 class=\"w-iconbox-title\">93% Grade 0-1<\/h5><div class=\"w-iconbox-text\"><p>Used as prophylaxis, 93% of patients remain pain-free and without limiting symptoms (CIPN &lt; grade 1). No impairment in everyday life.<\/p>\n<\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-iconbox iconpos_left style_circle color_custom align_left\"><div class=\"w-iconbox-icon\" style=\"font-size:1rem;--icon-color:#f7db49;--icon-bg-color:#ffffff;\"><i class=\"fas fa-plus\"><\/i><\/div><div class=\"w-iconbox-meta\"><h5 class=\"w-iconbox-title\">Fewer symptoms<\/h5><div class=\"w-iconbox-text\"><p>Even starting HILOTHERAPY<sup>\u00ae<\/sup> later in treatment will have an effect: the progression of severe CIPN is halted and it will prevent existing problems getting worse.<\/p>\n<\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-iconbox iconpos_left style_circle color_custom align_left\"><div class=\"w-iconbox-icon\" style=\"font-size:1rem;--icon-color:#f7db49;--icon-bg-color:#ffffff;\"><i class=\"fas fa-plus\"><\/i><\/div><div class=\"w-iconbox-meta\"><h5 class=\"w-iconbox-title\">Faster symptom-free<\/h5><div class=\"w-iconbox-text\"><p><strong>4 weeks after last chemotherapy:<\/strong><br \/>\n96% of all patients with prophylactic HILOTHERAPY<sup>\u00ae<\/sup> show only grade 0 &#8211; 1 symptoms.<\/p>\n<p><strong>Sustainable results:<\/strong><br \/>\n12 months after the end of chemotherapy, 98% of all patients are still symptom-free (CIPN &lt; grade 1).<\/p>\n<\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner us_custom_0eefff9f\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_huge\"><\/div><div class=\"w-btn-wrapper align_none\"><a class=\"w-btn us-btn-style_5\" target=\"_blank\" rel=\"nofollow\" href=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/09\/Arztbroschuere_CIPN_Englisch_s.pdf\"><span class=\"w-btn-label\">Download brochure<\/span><\/a><\/div><div class=\"w-btn-wrapper align_none\"><a class=\"w-btn us-btn-style_5\" target=\"_blank\" rel=\"nofollow\" href=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/09\/HT_ChemoCare_CIPN_Flyer_E_s.pdf\"><span class=\"w-btn-label\">Download Patient Information Flyer<\/span><\/a><\/div><div class=\"w-separator size_medium\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>Cross your heart. You try to do everything possible to reduce side effects of chemotherapy and better quality of life for your patients.<\/h3>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium color_alternate\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-grid us_carousel type_carousel layout_2519 preload_style_spinner\" id=\"us_grid_1\"><style>.layout_2519 .w-grid-item-h{}.layout_2519 .usg_hwrapper_1{margin-top:0.5rem!important}.layout_2519 .usg_post_custom_field_1{font-weight:700!important;line-height:1.5!important;margin-bottom:0!important}.layout_2519 .usg_post_custom_field_2{color:var(--color-content-faded)!important;font-size:0.9rem!important;line-height:1.5!important;margin-bottom:0!important}.layout_2519 .usg_vwrapper_2{padding-left:2rem!important;padding-top:3.5rem!important}.layout_2519 .usg_post_custom_field_3{color:#F7db49!important;font-size:3rem!important;line-height:1!important;position:absolute!important;left:0!important;top:0!important}<\/style><div class=\"w-grid-list owl-carousel valign_middle dotstyle_circle navstyle_circle arrows-ver-pos_middle arrows-hor-pos_on_sides_outside arrows-disabled_hide owl-responsive-2000\" style=\"--transition-duration:350ms;\">\t<article class=\"w-grid-item post-1180 us_testimonial type-us_testimonial status-publish hentry us_testimonial_category-chemo-en\" data-id=\"1180\">\r\n\t\t<div class=\"w-grid-item-h\">\r\n\t\t\t\t\t\t<div class=\"w-vwrapper usg_vwrapper_2 align_none valign_top\"><div class=\"w-post-elm post_custom_field usg_post_custom_field_3 has_text_color type_text  color_link_inherit\"><i class=\"far fa-quote-left\"><\/i><span class=\"w-post-elm-value\"><\/span><\/div><div class=\"w-post-elm post_content usg_post_content_1\"><p>Particularly in my hands, the feeling of numbness and the pains I had in my joints and tendons have almost completely disappeared. I put this miraculous improvement down to using your cooling glove-type hand cuffs. I often think back to the chemotherapy sessions when I was in treatment, which would go on for up to 8 hours, and how they would be so much more tolerable because I was now able to read. Before using this treatment, reading would have been unthinkable if I was using the ice packs that were offered to me at the clinic. Now I hope that, with time, I\u2019ll regain the sensitivity that I previously had in my feet.<\/p>\n<\/div><div class=\"w-hwrapper usg_hwrapper_1 align_none valign_middle\"><div class=\"w-vwrapper usg_vwrapper_1 align_none valign_top\"><div class=\"w-post-elm post_custom_field usg_post_custom_field_1 type_text us_testimonial_author\"><span class=\"w-post-elm-value\">Regina R.<\/span><\/div><div class=\"w-post-elm post_custom_field usg_post_custom_field_2 has_text_color type_text us_testimonial_role color_link_inherit\"><span class=\"w-post-elm-value\"><\/span><\/div><\/div><\/div><\/div>\t\t<\/div>\r\n\t\t\t<\/article>\r\n<\/div><div class=\"w-grid-carousel-json hidden\" onclick='return {&quot;carousel_settings&quot;:{&quot;aria_labels&quot;:{&quot;prev&quot;:&quot;Previous&quot;,&quot;next&quot;:&quot;Next&quot;},&quot;autoplayContinual&quot;:false,&quot;autoplayHoverPause&quot;:false,&quot;autoplayTimeout&quot;:5000,&quot;autoWidth&quot;:false,&quot;smartSpeed&quot;:350,&quot;margin&quot;:0,&quot;mouseDrag&quot;:true,&quot;rtl&quot;:false,&quot;slideBy&quot;:&quot;1&quot;,&quot;touchDrag&quot;:true,&quot;slideTransition&quot;:&quot;&quot;,&quot;responsive&quot;:{&quot;0&quot;:{&quot;autoHeight&quot;:false,&quot;autoplay&quot;:false,&quot;autoWidth&quot;:false,&quot;center&quot;:false,&quot;dots&quot;:false,&quot;items&quot;:1,&quot;loop&quot;:false,&quot;nav&quot;:false,&quot;stagePadding&quot;:0,&quot;slideBy&quot;:&quot;1&quot;},&quot;601&quot;:{&quot;items&quot;:1,&quot;autoplay&quot;:true,&quot;center&quot;:false,&quot;dots&quot;:false,&quot;nav&quot;:false,&quot;autoHeight&quot;:false,&quot;autoWidth&quot;:false,&quot;loop&quot;:false,&quot;stagePadding&quot;:0}}}}'><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_medium\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h2 style=\"text-align: center;\"><span style=\"color: #f7db49;\">About the disease<\/span><\/h2>\n<\/div><\/div><div class=\"w-separator size_medium\"><\/div><\/div><\/div><\/div><\/div><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><div class=\"xlarge-7 xlarge-offset-1 large-6 large-offset-1 medium-7 medium-offset-1 small-14 small-offset-1 cell\">\n<h3><strong>Polyneuropathy (CIPN) \/ hand-foot-syndrome (HFS) <\/strong><\/h3>\n<p>Chemotherapy is the most-feared of the treatments available to cancer patients. There is a great deal of fear due to the typical side effects: nausea, vomiting, possible infections, hair loss and, last but not least, the development of painful nerve damage in the hands and feet (<strong>polyneuropathy &#8211; CIPN<\/strong>). Whilst patients recover quickly from many side effects once chemotherapy has been completed; in the case of CIPN (<strong>c<\/strong>hemotherapy-<strong>i<\/strong>nduced <strong>p<\/strong>oly<strong>n<\/strong>europathy) patients are often faced with a long-term complication that continues over several years, significantly impacting their quality of life. CIPN particularly occurs in patients treated with taxane-containing drugs and platinum analogues. Other drugs, such as vinca alkaloids (incl. vincristine, or more rarely, vinblastine and vinorelbinel, 5- fluoropyrimidines (5-FU, capecitabinel, cvclophosphamide, cytarabine, doxorubicin, sorafenib and sunitinib may lead to these complications to a greater or lesser degree.<\/p>\n<p>&nbsp;<\/p>\n<h3><strong>A medical problem<\/strong><\/h3>\n<ul>\n<li>Up to 50% of patients develop severe HFS and polyneuropathy<\/li>\n<li>Patients are often forced to postpone therapy, or take a reduced dose (from just 2nd degree complications);<\/li>\n<li>some patients are even forced to stop treatment entirely.<\/li>\n<li>Complaints that can even persist years after therapy;<\/li>\n<li>it is not uncommon for symptoms to be irreversible.<\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><div class=\"xlarge-5 xlarge-offset-1 large-5 large-offset-2 medium-5 medium-offset-1 small-14 small-offset-1 cell\">\n<h3><strong>Symptoms of polyneuropathy\/ hand-foot syndrome<br \/>\n<\/strong><\/h3>\n<p>Polyneuropathy manifests itself as hypersensitivity to stimuli, pain, burning and\/or tingling in the hands and feet, loss of sensitivity (numbness), in some cases with associated problems relating to coordination of movement and balance. Those affected are barely able to distinguish between hot and cold, or this ability may even be lost completely. The primary effects include paraesthesia (abnormal sensation in skin] and pains. A special form of the disease, hand-foot syndrome, occurs when there is an associated inflammatory skin reaction in the hands and feet. Complaints are varied: painful areas of red skin, burning sensations (sometimes with skin abrasions), excess sensitivity to pain and at later stages, even numbness.Where acute symptoms present during chemotherapy, the treatment intervals must often be extended, the dose reduced, and, in the most severe cases, the treatment discontinued entirely.<\/p>\n<p>Grade 1: Tingling, painless swelling or erythema of the hands and\/or feet, or complaints that do not impact on the patient&#8217;s everyday activities.<\/p>\n<p>Grade 2: Painful erythema and swelling of the hands and\/or feet, and\/or complaints that impact on the patient&#8217;s everyday activities.<\/p>\n<p>Grade 3: A moist peeling of the skin, ulceration, blistering and severe pain in the hands and\/or feet, and\/ol severe symptoms which make it impossible for the patient to work or carry out the activities of daily life.<\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium color_alternate\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_medium\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h2 style=\"text-align: center;\"><span style=\"color: #f7db49;\">How does it come about?<\/span><\/h2>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><\/div><\/div><\/div><\/div><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Polyneuropathy<\/strong><\/p>\n<p>The mechanism by which polyneuropathy occurs relies on two processes:<\/p>\n<ol>\n<li>direct damage to sensory neurons (nerve cells) due to the chemotherapy drug, partly due to oxidative stress, which is triggered by the drug.<\/li>\n<li>Inflammatory processes in the nervous system. Where exactly the damage occurs to the sensory neurons depends primarily on the specific chemotherapy drug administered.<\/li>\n<\/ol>\n<p>In addition to the classical chemotherapy drugs, even new targeted approaches (e.g with antibody conjugates) similarly lead to CIPN (Younes, Clin Oncol, 2012], a fact which is indicative of the continuing and even increasing relevance of CIPN as a side effect of oncological therapies.<\/p>\n<p>According to current understanding, the cause behind these symptoms is blood supply through enlarged capillaries to the nerve cells of the sensory nerve system. There is a different protein composition of the capillary cell wall, which becomes more permeable to certain chemotherapy drugs. This leads to the drugs causing significant damage to nerve cells.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_large\"><\/div><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"870\" height=\"674\" src=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/11\/Chemo_Grafiken_1_1.png\" class=\"attachment-large size-large\" alt=\"Polyneuropatie - Sch\u00e4den am Sensorchen Neuron - Grafik\" loading=\"lazy\" \/><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-separator size_large\"><\/div><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"443\" height=\"320\" src=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/11\/Chemo_Grafiken_2.png\" class=\"attachment-large size-large\" alt=\"Chemo - Chemotherapeutikum - Grafik\" loading=\"lazy\" \/><\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_medium\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The exact mechanism through which hand-foot syndrome develops is not fully understood. It is assumed that a proportion of the chemotherapy drugs are released onto the skin surface via the sweat glands where it contacts with oxygen to form &#8220;free radicals&#8221;. These free radicals damage tissue cells of the skin, with damage being particularly severe where the skin has a more callous quality and the substances are absorbed like a sponge: on the palm of the hand and the sole of the foot.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium with_img\"><div class=\"l-section-img\" role=\"img\" aria-label=\"Hintergrundbild Ring hellgelb\" data-img-width=\"653\" data-img-height=\"732\" style=\"background-image: url(https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/06\/circle-hilotherm-yellow.png);background-position: top right;background-repeat: no-repeat;background-size: auto;\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"683\" height=\"1024\" src=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/06\/chemo_care_doppel-683x1024.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/06\/chemo_care_doppel-683x1024.png 683w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/06\/chemo_care_doppel-200x300.png 200w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/06\/chemo_care_doppel-100x150.png 100w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/06\/chemo_care_doppel-600x900.png 600w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2020\/06\/chemo_care_doppel.png 1000w\" sizes=\"auto, (max-width: 683px) 100vw, 683px\" \/><\/div><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h2>Using the device<\/h2>\n<p>HILOTHERAPY<sup>\u00ae<\/sup> functions using a combination of the HILOTHERM ChemoCare <sup>CIPN<\/sup> device, specially-designed cuffs for hands and feet, and a closed-loop circulation system through which a cooling medium flows. The processor-controlled unit ensures a stable temperature for the entire duration of the treatment, even over a period of many hours.<\/p>\n<h5><b>Controlled cooling of the extremities during chemotherapy.<\/b><\/h5>\n<p>For the prevention of Polyneuropathie (CIPN) and Hand-Foot-Syndrom (HFS) both hands and feet are being cooled during every chemotherapy treatment.<\/p>\n<h5><b>Simple. Compatible. <\/b><b>Highly effective.<\/b><\/h5>\n<p><a class=\"button--arrow button--arrow\" href=\"https:\/\/www.hilotherm.com\/produktuebersicht\/#chemocare\" target=\"_self\" rel=\"noopener noreferrer\">HILOTHERM ChemoCare CIPN Device<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium color_alternate\"><div class=\"l-section-overlay\" style=\"background:rgba(255,255,255,0.85)\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_small\"><\/div><div class=\"g-cols wpb_row via_flex valign_middle type_default stacking_default\"><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator size_small\"><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h5>Studies show:<\/h5>\n<p>Without prophylactic HILOTHERAPY\u00ae 90% of all patients inside develop symptoms of CIPN and Hand-Foot-Syndrom (Grade 1 &#8211; 3) \u2013 50% of them severe (Grade 2\/3).<\/p>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-6 wpb_column vc_column_container\"><div class=\"vc_column-inner us_custom_bb7967fc\"><div class=\"vc_column-overlay\" style=\"background:rgba(247,219,73,0.80)\"><\/div><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h5>Get the best results when starting with the first chemotherapy treatment:<\/h5>\n<p>The earlier you start HILOTHERAPY<sup>\u00ae<\/sup>, the better. Grade 2 and 3 toxicities can be be greatly reduced or avoided.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_auto width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"w-separator us_custom_f8f9c8af size_custom\" style=\"height:5px\"><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-2 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><div class=\"vc_col-sm-8 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"g-cols wpb_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-12 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h2>FAQ<\/h2>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs style_default switch_click accordion has_scrolling\" style=\"--sections-title-size:inherit\"><div class=\"w-tabs-sections titles-align_none icon_chevron cpos_right\"><div class=\"w-tabs-section\" id=\"d8cc\"><button class=\"w-tabs-section-header with_icon\" aria-controls=\"content-d8cc\" aria-expanded=\"false\"><i class=\"fas fa-question\"><\/i><div class=\"w-tabs-section-title\">How can I use the device? At home? Do I have to buy it? Are there financing options? Can I just rent the device?<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-d8cc\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The ChemoCare device has been developed for use in in-patients in hospitals and clinics and is applied before, during and after a chemotherapy treatment session. Hospitals\/clinics can buy a device outright, with finance, or on a lease. Simply get in touch with one of our team.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"h9d8\"><button class=\"w-tabs-section-header with_icon\" aria-controls=\"content-h9d8\" aria-expanded=\"false\"><i class=\"fas fa-question\"><\/i><div class=\"w-tabs-section-title\">My treatment doctor does not have a device.\u2026.. What can I do?<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-h9d8\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>We would be delighted to contact your doctor in order to make it possible for you to use the device. Please get in touch with one of our team.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"yac6\"><button class=\"w-tabs-section-header with_icon\" aria-controls=\"content-yac6\" aria-expanded=\"false\"><i class=\"fas fa-question\"><\/i><div class=\"w-tabs-section-title\">Do l have to use HILOTHERAPY\u00ae as a hospital\/clinic in-patient?<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-yac6\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>HILOTHERAPY<sup>\u00ae<\/sup> is used immediately prior to, during, and following a chemotherapy treatment session at the respective clinic\/hospital.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"gbc4\"><button class=\"w-tabs-section-header with_icon\" aria-controls=\"content-gbc4\" aria-expanded=\"false\"><i class=\"fas fa-question\"><\/i><div class=\"w-tabs-section-title\">Will the costs for treatment he covered by the German statutory health insurers?<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-gbc4\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Unfortunately, the German statutory health insurers do not cover costs for this treatment. We would also be delighted to give vou turther intormation regarding costs tor the treatment.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-separator size_small\"><\/div><\/div><\/div><\/div><div class=\"vc_col-sm-2 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row height_medium color_primary\"><div class=\"l-section-overlay\" style=\"background:#f9db45\"><\/div><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_flex valign_top type_default stacking_default\"><div class=\"vc_col-sm-2 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><div class=\"vc_col-sm-8 wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h2>Good to know (DE) \u2013 with Dr. Trudi Schaper<\/h2>\n<\/div><\/div><div class=\"w-separator size_small\"><\/div><div class=\"w-grid us_carousel type_carousel layout_blog_1 preload_style_spinner open_items_in_popup items_3\" id=\"us_grid_2\" style=\"--items:3;--gap:1.5rem;\"><style>.layout_blog_1 .w-grid-item-h{}.layout_blog_1 .usg_post_image_1{margin-bottom:0.5rem!important}.layout_blog_1 .usg_post_title_1{font-size:1rem!important}<\/style><div class=\"w-grid-list owl-carousel valign_stretch dotstyle_circle navstyle_circle arrows-ver-pos_middle arrows-hor-pos_on_sides_outside arrows-disabled_hide owl-responsive-2000 with_dots with_arrows\" style=\"--transition-duration:350ms;--arrows-size:1.5rem;--arrows-hor-offset:calc(0px + 1.5rem);--arrows-gap:10px;\">\t<article class=\"w-grid-item post-2373 post type-post status-publish format-video has-post-thumbnail hentry category-chemocare-faq post_format-post-format-video\" data-id=\"2373\">\r\n\t\t<div class=\"w-grid-item-h\">\r\n\t\t\t\t\t\t<div class=\"w-post-elm post_image usg_post_image_1 stretched\"><a href=\"https:\/\/www.hilotherm.com\/en\/vorteile-kontrollierter-hand-fuss-kuehlung\/\" aria-label=\"Vorteile kontrollierter Hand-Fu\u00df-Ku\u0308hlung\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/06\/erklaerung-1024x576.jpg\" class=\"attachment-large size-large wp-post-image\" alt=\"\" srcset=\"https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/06\/erklaerung-1024x576.jpg 1024w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/06\/erklaerung-300x169.jpg 300w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/06\/erklaerung-600x338.jpg 600w, https:\/\/www.hilotherm.com\/wp-content\/uploads\/2022\/06\/erklaerung.jpg 1920w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/div><h2 class=\"w-post-elm post_title usg_post_title_1 entry-title color_link_inherit\"><a 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